Detalhe da pesquisa
1.
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.
Cell
; 184(12): 3143-3162.e32, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34004147
2.
Rationally designed chimeric PI3K-BET bromodomain inhibitors elicit curative responses in MYC-driven lymphoma.
Proc Natl Acad Sci U S A
; 120(36): e2306414120, 2023 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643213
3.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Nature
; 560(7717): 253-257, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30069049
4.
Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas.
Blood
; 121(15): 2964-74, 2013 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-23403624
5.
Stepwise progression of ß-selection during T cell development involves histone deacetylation.
Life Sci Alliance
; 6(1)2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36283704
6.
The Combination of Curaxin CBL0137 and Histone Deacetylase Inhibitor Panobinostat Delays KMT2A-Rearranged Leukemia Progression.
Front Oncol
; 12: 863329, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35677155
7.
Defining the target specificity of ABT-737 and synergistic antitumor activities in combination with histone deacetylase inhibitors.
Blood
; 113(9): 1982-91, 2009 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-19060243
8.
The histone deacetylase inhibitors LAQ824 and LBH589 do not require death receptor signaling or a functional apoptosome to mediate tumor cell death or therapeutic efficacy.
Blood
; 114(2): 380-93, 2009 Jul 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19383971
9.
Serine Biosynthesis Is a Metabolic Vulnerability in FLT3-ITD-Driven Acute Myeloid Leukemia.
Cancer Discov
; 11(6): 1582-1599, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33436370
10.
AZD4320, A Dual Inhibitor of Bcl-2 and Bcl-xL, Induces Tumor Regression in Hematologic Cancer Models without Dose-limiting Thrombocytopenia.
Clin Cancer Res
; 26(24): 6535-6549, 2020 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-32988967
11.
Characterisation of the novel apoptotic and therapeutic activities of the histone deacetylase inhibitor romidepsin.
Mol Cancer Ther
; 7(5): 1066-79, 2008 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-18483296
12.
Cloning and characterisation of Ifi206: a new murine HIN-200 family member.
J Cell Biochem
; 103(4): 1270-82, 2008 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17786933
13.
How do tumor cells respond to HDAC inhibition?
FEBS J
; 283(22): 4032-4046, 2016 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27112360
14.
Therapeutic Response to Non-genotoxic Activation of p53 by Nutlin3a Is Driven by PUMA-Mediated Apoptosis in Lymphoma Cells.
Cell Rep
; 14(8): 1858-66, 2016 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26904937
15.
BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members.
Mol Cancer Ther
; 15(9): 2030-41, 2016 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-27406984
16.
Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.
Cancer Cell
; 30(1): 59-74, 2016 07 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-27374225
17.
Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in hematological tumors.
Cold Spring Harb Protoc
; 2014(10): pdb.prot082511, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275108
18.
Fluorodeoxyglucose-based positron emission tomography imaging to monitor drug responses in solid tumors.
Cold Spring Harb Protoc
; 2014(10): pdb.prot082529, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25275109
19.
Detection of apoptotic cells using immunohistochemistry.
Cold Spring Harb Protoc
; 2014(11): 1196-201, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25368310
20.
Detection of apoptotic cells using propidium iodide staining.
Cold Spring Harb Protoc
; 2014(11): 1202-6, 2014 Nov 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-25368311